In conducting business on the Company’s behalf, there are certain general principles that each Amgen staff member should follow. Underlying all of these principles is Amgen’s basic policy of continually striving to do the right thing. Please refer to the current General Business Conduct Policy for additional details regarding the policy and the obligations of individuals subject to the policy.

In addition, there are several areas that raise specific legal concerns. Scrupulous attention should be paid to compliance with all laws and policies in these areas, as well as any other applicable laws and policies that relate to how Amgen conducts its business. If you have any reason to believe that any of the following laws or policies have been violated, you should immediately report the violation to the Business Conduct Hotline (see the “Where to Turn for Help or Report Concerns” section for contact information).