Osteoporosis, or bone disease, is characterized by low bone mass and structural deterioration of bone tissues. It can lead to bone fragility and an increased susceptibility to fractures, especially of the hip, spine and wrist. Osteoporotic fractures, particularly spinal fractures, can cause patients disabling pain.

Approximately 44 million Americans age 50 or older have osteoporosis or are at risk for developing it. About 10 million Americans currently suffer from osteoporosis.

Osteoporosis occurs as bones become less dense. Throughout a person’s life, bones are constantly being renewed. As people age, old bone continues to be removed, but new bone formation starts to lag behind. The result is a gradual and steady decrease in the amount of bone material, which can lead to osteoporosis. As bone density decreases, bones become weaker and more likely to fracture.